Anaplastic Kaposi's sarcoma: a study of eight patients.
Identifieur interne : 012F27 ( Main/Exploration ); précédent : 012F26; suivant : 012F28Anaplastic Kaposi's sarcoma: a study of eight patients.
Auteurs : Athanasia Tourlaki [Italie] ; Sebastiano Recalcati [Italie] ; Vinicio Boneschi [Italie] ; Francesca Gaiani [Italie] ; Antonella Colombo [Italie] ; Roberta Mancuso [Italie] ; Lucia Brambilla [Italie]Source :
- European journal of dermatology : EJD [ 1952-4013 ]
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Sarcome de Kaposi, Tumeurs cutanées.
- Adulte d'âge moyen, Femelle, Humains, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus.
English descriptors
- KwdEn :
- MESH :
- pathology : Sarcoma, Kaposi, Skin Neoplasms.
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged.
Abstract
Anaplastic Kaposi's sarcoma is a rare form of vascular tumor, clinically notable for its high local aggressiveness, propensity for deep invasion and increased metastatic capacity. This cancer arises in patients with a history of Kaposi's sarcoma (KS) and because of its rarity, few clinical data are available. To gain insight into this rare disease, we present eight cases of anaplastic KS which developed in eight out of 578 (1.4%) patients suffering from classic KS and followed in our department over a period of 30 years. Clinically, seven patients presented with deep tissue invasion. All the anaplastic cases underwent systemic chemotherapy and five received a non-conservative surgical therapy. Four (50%) out of the eight patients are now in complete remission, while three (37.5%) of them died of anaplastic Kaposi's sarcoma and one (12.5%) died of pneumonia after an excellent response to chemotherapy alone. Our findings suggest that in patients with anaplastic KS, non-conservative surgery associated with systemic chemotherapy may lead to complete remission, avoiding the poor outcome reported in previous cases.
DOI: 10.1684/ejd.2013.2019
PubMed: 23783037
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001A66
- to stream PubMed, to step Curation: 001A66
- to stream PubMed, to step Checkpoint: 001A66
- to stream Ncbi, to step Merge: 005A49
- to stream Ncbi, to step Curation: 005A49
- to stream Ncbi, to step Checkpoint: 005A49
- to stream Main, to step Merge: 014146
- to stream Main, to step Curation: 012F27
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Anaplastic Kaposi's sarcoma: a study of eight patients.</title><author><name sortKey="Tourlaki, Athanasia" sort="Tourlaki, Athanasia" uniqKey="Tourlaki A" first="Athanasia" last="Tourlaki">Athanasia Tourlaki</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Recalcati, Sebastiano" sort="Recalcati, Sebastiano" uniqKey="Recalcati S" first="Sebastiano" last="Recalcati">Sebastiano Recalcati</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boneschi, Vinicio" sort="Boneschi, Vinicio" uniqKey="Boneschi V" first="Vinicio" last="Boneschi">Vinicio Boneschi</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Gaiani, Francesca" sort="Gaiani, Francesca" uniqKey="Gaiani F" first="Francesca" last="Gaiani">Francesca Gaiani</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Colombo, Antonella" sort="Colombo, Antonella" uniqKey="Colombo A" first="Antonella" last="Colombo">Antonella Colombo</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mancuso, Roberta" sort="Mancuso, Roberta" uniqKey="Mancuso R" first="Roberta" last="Mancuso">Roberta Mancuso</name><affiliation wicri:level="3"><nlm:affiliation>Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation, ONLUS, IRCCS, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation, ONLUS, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Brambilla, Lucia" sort="Brambilla, Lucia" uniqKey="Brambilla L" first="Lucia" last="Brambilla">Lucia Brambilla</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2013 May-Jun</MedlineDate></PubDate></date><idno type="RBID">pubmed:23783037</idno><idno type="pmid">23783037</idno><idno type="doi">10.1684/ejd.2013.2019</idno><idno type="wicri:Area/PubMed/Corpus">001A66</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001A66</idno><idno type="wicri:Area/PubMed/Curation">001A66</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001A66</idno><idno type="wicri:Area/PubMed/Checkpoint">001A66</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001A66</idno><idno type="wicri:Area/Ncbi/Merge">005A49</idno><idno type="wicri:Area/Ncbi/Curation">005A49</idno><idno type="wicri:Area/Ncbi/Checkpoint">005A49</idno><idno type="wicri:Area/Main/Merge">014146</idno><idno type="wicri:Area/Main/Curation">012F27</idno><idno type="wicri:Area/Main/Exploration">012F27</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Anaplastic Kaposi's sarcoma: a study of eight patients.</title><author><name sortKey="Tourlaki, Athanasia" sort="Tourlaki, Athanasia" uniqKey="Tourlaki A" first="Athanasia" last="Tourlaki">Athanasia Tourlaki</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Recalcati, Sebastiano" sort="Recalcati, Sebastiano" uniqKey="Recalcati S" first="Sebastiano" last="Recalcati">Sebastiano Recalcati</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boneschi, Vinicio" sort="Boneschi, Vinicio" uniqKey="Boneschi V" first="Vinicio" last="Boneschi">Vinicio Boneschi</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Gaiani, Francesca" sort="Gaiani, Francesca" uniqKey="Gaiani F" first="Francesca" last="Gaiani">Francesca Gaiani</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Colombo, Antonella" sort="Colombo, Antonella" uniqKey="Colombo A" first="Antonella" last="Colombo">Antonella Colombo</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mancuso, Roberta" sort="Mancuso, Roberta" uniqKey="Mancuso R" first="Roberta" last="Mancuso">Roberta Mancuso</name><affiliation wicri:level="3"><nlm:affiliation>Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation, ONLUS, IRCCS, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation, ONLUS, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Brambilla, Lucia" sort="Brambilla, Lucia" uniqKey="Brambilla L" first="Lucia" last="Brambilla">Lucia Brambilla</name><affiliation wicri:level="1"><nlm:affiliation>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>U.O. Dermatologia, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, via Pace 9, 20122 Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author></analytic><series><title level="j">European journal of dermatology : EJD</title><idno type="eISSN">1952-4013</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Sarcoma, Kaposi (pathology)</term><term>Skin Neoplasms (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Sarcome de Kaposi (anatomopathologie)</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Tumeurs cutanées (anatomopathologie)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Sarcome de Kaposi</term><term>Tumeurs cutanées</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Sarcoma, Kaposi</term><term>Skin Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Anaplastic Kaposi's sarcoma is a rare form of vascular tumor, clinically notable for its high local aggressiveness, propensity for deep invasion and increased metastatic capacity. This cancer arises in patients with a history of Kaposi's sarcoma (KS) and because of its rarity, few clinical data are available. To gain insight into this rare disease, we present eight cases of anaplastic KS which developed in eight out of 578 (1.4%) patients suffering from classic KS and followed in our department over a period of 30 years. Clinically, seven patients presented with deep tissue invasion. All the anaplastic cases underwent systemic chemotherapy and five received a non-conservative surgical therapy. Four (50%) out of the eight patients are now in complete remission, while three (37.5%) of them died of anaplastic Kaposi's sarcoma and one (12.5%) died of pneumonia after an excellent response to chemotherapy alone. Our findings suggest that in patients with anaplastic KS, non-conservative surgery associated with systemic chemotherapy may lead to complete remission, avoiding the poor outcome reported in previous cases.</div></front></TEI><affiliations><list><country><li>Italie</li></country><region><li>Lombardie</li></region><settlement><li>Milan</li></settlement></list><tree><country name="Italie"><region name="Lombardie"><name sortKey="Tourlaki, Athanasia" sort="Tourlaki, Athanasia" uniqKey="Tourlaki A" first="Athanasia" last="Tourlaki">Athanasia Tourlaki</name></region><name sortKey="Boneschi, Vinicio" sort="Boneschi, Vinicio" uniqKey="Boneschi V" first="Vinicio" last="Boneschi">Vinicio Boneschi</name><name sortKey="Brambilla, Lucia" sort="Brambilla, Lucia" uniqKey="Brambilla L" first="Lucia" last="Brambilla">Lucia Brambilla</name><name sortKey="Colombo, Antonella" sort="Colombo, Antonella" uniqKey="Colombo A" first="Antonella" last="Colombo">Antonella Colombo</name><name sortKey="Gaiani, Francesca" sort="Gaiani, Francesca" uniqKey="Gaiani F" first="Francesca" last="Gaiani">Francesca Gaiani</name><name sortKey="Mancuso, Roberta" sort="Mancuso, Roberta" uniqKey="Mancuso R" first="Roberta" last="Mancuso">Roberta Mancuso</name><name sortKey="Recalcati, Sebastiano" sort="Recalcati, Sebastiano" uniqKey="Recalcati S" first="Sebastiano" last="Recalcati">Sebastiano Recalcati</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 012F27 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 012F27 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:23783037
|texte= Anaplastic Kaposi's sarcoma: a study of eight patients.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23783037" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |